The strategy I use every year is not to worry about bye weeks. I try to get as many as possible on bye the same week (while still fielding a team). I would rather suck for a week, instead of patchworking a lineup for 5-6 weeks. I have Kitna, Roy Williams, Gore, Nedney, and H Miller gone.
This is my lineup this week in a yardage league:
Schaub
Portis, Ward (or one of the Atl RB's)
Housh, A Davis
Pick up TE
Ravens kicker
My opponent has people on bye and loses SJax. Nice thing is the rest of the year, I have one or two on byes and thats it.